New insights into the combined effects of aflatoxin B1 and Eimeria ovinoidalis on uterine function by disrupting the gut–blood–reproductive axis in sheep
These findings reveal for the first time that the combined effects of AFB1 and E. ovinoidalis on sheep uterine function operate at the level of the gut-blood-reproductive axis. This suggests that regulating gut microbiota and its metabolites may represent a potential therapeutic strategy for addressing mycotoxins and coccidia-co-induced female reproductive toxicity.
Authors
- Fuchun Jian (ORCID: https://orcid.org/0000-0001-9481-2277)
- Bowen Xu (ORCID: https://orcid.org/0009-0005-9150-8145)
- Tao-Jing Yue
- Jiakui Li (ORCID: https://orcid.org/0000-0002-6065-6648)
- Wenli Ding
- Kaili Liu (ORCID: https://orcid.org/0000-0002-4167-8243)
- Shucheng Huang (ORCID: https://orcid.org/0000-0003-3163-8616)
- Pan Chen (ORCID: https://orcid.org/0000-0003-3429-1275)
- Yanan Lu (ORCID: https://orcid.org/0000-0002-7555-4337)
- Sijin Li
Institutions
- Huazhong Agricultural University (CN)
- Henan Agricultural University (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s40168-024-01966-y
- Citations
- 10
- Primary Topic
- Coccidia and coccidiosis research
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation