HDAC10 switches NLRP3 modification from acetylation to ubiquitination and attenuates acute inflammatory diseases
This study indicated that HDAC10 switched NLRP3 modification from acetylation to ubiquitination and attenuated acute inflammatory diseases, thus it provided a potential therapeutic strategy for NLRP3 inflammasome-associated diseases by targeting HDAC10.
Authors
- Yueke Lin (ORCID: https://orcid.org/0000-0003-1273-1006)
- Haocheng Xuan
- Dapeng Ma (ORCID: https://orcid.org/0000-0003-1385-100X)
- Xinyi Zhu (ORCID: https://orcid.org/0000-0002-7361-8958)
- Lihui Han (ORCID: https://orcid.org/0000-0003-1030-2232)
- Zhenzhi Qin (ORCID: https://orcid.org/0000-0001-7301-4743)
- Caiyu Sun (ORCID: https://orcid.org/0000-0002-3001-5364)
- Xiuling Cui
- W. F. Mader (ORCID: https://orcid.org/0000-0002-7344-998X)
- Min Yang (ORCID: https://orcid.org/0000-0002-2529-6501)
Institutions
- Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s12964-024-01992-1
- Citations
- 12
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province