A Facile and Highly Efficient One-Pot Synthesis of Symmetrical and Unsymmetrical Aldazines Using Reusable MMZHY Solid Acid Catalyst

A detailed study on one-pot synthesis of 2,3-diaza-1,3-butadiene derivatives from various aromatic aldehydes and hydrazine by using MMZHY solid acid catalyst is reported. The role of the bifunctional nature of MMZHY and the effect of metal ions in the catalyst are described with a supportive mechanism. Both sym­metrical and unsymmetrical aldazines (hydrazone free) were prepared with excellent yields and characterized by 1H and 13C NMR spectra. The other advantages of the catalytic system like its easy preparation by the bottom-up method, reusability, multiporous nature which reduces diffusional limitations, easy separation, and mild reaction conditions with higher yield of products are also highlighted.