Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway
GpS ameliorates Sev-induced neurotoxicity and cognitive dysfunction by modulating the PI3K/Akt/mTOR pathway and alleviating neuronal apoptosis and oxidative stress.
Authors
- Lijuan Lin (ORCID: https://orcid.org/0009-0004-7523-8993)
- Chenhui Zhu (ORCID: https://orcid.org/0000-0002-7602-0804)
- Junren Chen
- Wei Huang
- Liu Yang (ORCID: https://orcid.org/0000-0001-6848-7669)
- Peishuang Yu
- Bing Yan
Institutions
- Central People's Hospital of Zhanjiang (CN)
Publication Details
- Journal
- Clinics
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.clinsp.2024.100560
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00