Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway

GpS ameliorates Sev-induced neurotoxicity and cognitive dysfunction by modulating the PI3K/Akt/mTOR pathway and alleviating neuronal apoptosis and oxidative stress.

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Publication Details

Journal
Clinics
Published
2024-12-20
DOI
https://doi.org/10.1016/j.clinsp.2024.100560
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway

Lijuan Lin, Chenhui Zhu, Junren Chen, Wei Huang et al.
Clinics
Anesthesia and Neurotoxicity Research
article

Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway

Lijuan Lin, Chenhui Zhu, Junren Chen, Wei Huang, Liu Yang, Peishuang Yu, Bing Yan
article en

Abstract

GpS ameliorates Sev-induced neurotoxicity and cognitive dysfunction by modulating the PI3K/Akt/mTOR pathway and alleviating neuronal apoptosis and oxidative stress.

ClinicsVol. 80
Central People's Hospital of Zhanjiang (CN)
Zero hunger
Openalex Percentile: Top 73%
Anesthesia and Neurotoxicity Research
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Gyosaponin ameliorates sevoflurane anesthesia-induced cognitive dysfunction and neuronal apoptosis in rats through modulation of the PI3K/AKT/mTOR pathway — Lijuan Lin, Chenhui Zhu, et al. · Clinics (2024) | TGRS Research Map | TGRS