Disruption of gamete fusion alters the sperm-egg ratio at gamete interaction
These findings indicate that genetic ablation of Cd9 leads to an imbalance in the 1:1 sperm-egg ratio observed within the ampulla. This information may set the foundation for future studies with the aim to identify the specific mechanisms that sperm use to locate unfertilized eggs and whether they become ineffective when gamete fusion is prevented.
Authors
- Matteo Avella (ORCID: https://orcid.org/0000-0003-0104-3304)
- Eva Stickler
Institutions
- Qatar Airways (Qatar) (QA)
- Sidra Medical and Research Center (QA)
- University of Tulsa (US)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s12967-024-05948-4
- Citations
- 1
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- University of Tulsa
- Sidra Medicine
- National Institutes of Health