[Herpes zoster : vaccination and management of satellite lesions in immunocompromised patients].
Shingles, also termed herpes zoster (HZ), is due to the reactivation of the varicella zoster virus (VZV) in a dorsal root nerve ganglion with an intra-axonal passage of the virus to a predetermined dermatome. The risk of HZ increases with age, as well as the morbidity risks. The most feared complication is post-herpetic neuralgia, defined as persisting pain sensations three months after the resolution of the skin lesions. Those risks are even more important in the immunocompromised patient. Currently a recombinant vaccine against HZ reactivation is available with an excellent safety profile. It has demonstrated a very high vaccine protection achieving 97 % for preventing HZ and its complications. A patient presented severe facial HZ with a large number of HZ satellite lesions disseminated over the entire tegumentum. These satellite lesions are a reliable clinical marker for HZ with a high risk for complications. This case underlines the risk of morbidity in the elderly immunocompromised patient as well the fact that HZ is a vaccine preventable disease, currently reimbursed, but not well-known.
Authors
- Arjen Nikkels (ORCID: https://orcid.org/0000-0001-5240-4806)
- Thibaut Delahaye (ORCID: https://orcid.org/0009-0002-7896-6895)
Institutions
- Centre Hospitalier Universitaire de Liège (BE)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-01
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article