[Effect and related mechanism of acetate in alleviating acute kidney injury in septic rats through G-protein coupled receptor 43].

Acetate can ameliorate sepsis-induced AKI, the mechanism may be related to the activation of AMPK/SIRT1/PGC-1α pathway by GPR43.

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Publication Details

Journal
PubMed
Published
2024-11-01
DOI
https://doi.org/10.3760/cma.j.cn121430-20231025-00902
Primary Topic
Renal function and acid-base balance
Type
article
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article

[Effect and related mechanism of acetate in alleviating acute kidney injury in septic rats through G-protein coupled receptor 43].

Xingyu Shi, Ruifeng Chai, Jiayu Xing, Jian Li et al.
PubMed
Renal function and acid-base balance
article

[Effect and related mechanism of acetate in alleviating acute kidney injury in septic rats through G-protein coupled receptor 43].

Xingyu Shi, Ruifeng Chai, Jiayu Xing, Jian Li, Yibin Wang, Xiangyou Yu
article en

Abstract

Acetate can ameliorate sepsis-induced AKI, the mechanism may be related to the activation of AMPK/SIRT1/PGC-1α pathway by GPR43.

PubMedVol. 36(11)
Xinjiang Medical University (CN), First Affiliated Hospital of Xinjiang Medical University (CN)
Renal function and acid-base balance
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