Association between osteoarthritis-related serum biochemical markers over 10–13 years and knee symptoms in middle-aged adults
Cumulative COMP, baseline MMP-3, and changes in HA were associated with knee pain over a a 10-13 year follow-up. These markers may help predict future knee symptoms in middle-aged adults.
Authors
- John Burgess (ORCID: https://orcid.org/0000-0003-4748-9571)
- Graeme Jones (ORCID: https://orcid.org/0000-0002-9814-0006)
- Changhai Ding (ORCID: https://orcid.org/0000-0002-9479-730X)
- Lyn March (ORCID: https://orcid.org/0000-0003-1736-8111)
- Alison Venn (ORCID: https://orcid.org/0000-0001-7090-1398)
- Christopher Leigh Blizzard (ORCID: https://orcid.org/0000-0002-9541-6943)
- Brooklyn J. Fraser (ORCID: https://orcid.org/0000-0002-1752-5431)
- Ambrish Singh (ORCID: https://orcid.org/0000-0002-4618-7507)
- Flavia Cicuttini
- Benny Antony (ORCID: https://orcid.org/0000-0002-7725-8822)
- Venkat Parameswaran
Institutions
- The University of Sydney (AU)
- University of Tasmania (AU)
- Royal North Shore Hospital (AU)
- Royal Hobart Hospital (AU)
- Zhujiang Hospital (CN)
- Alberta Bone and Joint Health Institute (CA)
- Monash University (AU)
- Southern Medical University (CN)
Publication Details
- Journal
- Modern Rheumatology
- Published
- 2024-12-17
- DOI
- https://doi.org/10.1093/mr/roae113
- Citations
- 3
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Royal Hobart Hospital Research Foundation
- University of Tasmania
- Medical Research Council
- National Health and Medical Research Council