Investigating the common genetic architecture and causality of metabolic disorders with neurodegenerative diseases
Our findings reveal a shared genetic basis, pleiotropic loci, and potential causal relationships between metabolic dysfunction and neurodegenerative diseases. These insights highlight the biological connections underlying their phenotypic association and offer implications for future research to reduce the risk of neurodegenerative diseases.
Authors
- Hao Dai (ORCID: https://orcid.org/0000-0003-0963-3296)
- Sipeng Shen (ORCID: https://orcid.org/0000-0003-0436-4736)
- Jinglan Dai
- Hao Hong (ORCID: https://orcid.org/0000-0002-7801-7668)
- Jingyi Zhao
- Pan Gu
- Kuanfeng Xu (ORCID: https://orcid.org/0000-0002-6761-2349)
- Tao Yang (ORCID: https://orcid.org/0000-0001-6375-3622)
- Qi Fu (ORCID: https://orcid.org/0000-0002-1626-0419)
Institutions
- Jiangsu Cancer Hospital (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1111/dom.16130
- Citations
- 4
- Primary Topic
- Neurological diseases and metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.99
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Nanjing Medical University