Baicalin alleviates intestinal inflammation and microbial disturbances by regulating Th17/Treg balance and enhancing Lactobacillus colonization in piglets
Baicalin supplementation effectively alleviates E. coli-induced intestinal inflammation and microbial disturbances in piglets by enhancing beneficial Lactobacillus colonization, counteracting inflammatory mediators, and regulating immune-related gene expression and the Th17/Treg balance. These findings highlight baicalin's potential in alleviating intestinal inflammation.
Authors
- Qiugang Ma (ORCID: https://orcid.org/0000-0001-7260-3765)
- Ruqing Zhong (ORCID: https://orcid.org/0000-0003-0494-6699)
- Chengzeng Luo (ORCID: https://orcid.org/0000-0002-3284-6049)
- Shunfen Zhang (ORCID: https://orcid.org/0000-0003-4895-9299)
- Liang Chen (ORCID: https://orcid.org/0000-0002-3605-8883)
- Junhong Wang (ORCID: https://orcid.org/0000-0001-7714-5257)
- Huixin Wang (ORCID: https://orcid.org/0000-0002-2081-1332)
- Hongfu Zhang (ORCID: https://orcid.org/0000-0001-8790-2709)
- Kai Li (ORCID: https://orcid.org/0000-0001-8601-9180)
Institutions
- Chinese Academy of Agricultural Sciences (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s40104-024-01126-0
- Citations
- 8
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 1.92
Funders
- National Natural Science Foundation of China
- Chinese Academy of Agricultural Sciences
- Agricultural Science and Technology Innovation Program