In vivo retinal melanin detection with the calibrated depolarization index in polarization-sensitive optical coherence tomography
Our proposed calibration method enhanced the visualization of depolarizing structures in PS-OCT, which can be generalized to all kinds of polarization-sensitive imaging and can potentially monitor melanin in healthy and pathological eyes.
Authors
- Leopold F. Schmetterer (ORCID: https://orcid.org/0000-0002-7189-1707)
- Jacqueline Chua (ORCID: https://orcid.org/0000-0002-6474-5293)
- J. S. Cheong (ORCID: https://orcid.org/0009-0001-9919-8779)
- Mengyuan Ke (ORCID: https://orcid.org/0000-0002-2574-8432)
- Liqin Jiang (ORCID: https://orcid.org/0000-0002-9751-7510)
- Veluchamy A. Barathi (ORCID: https://orcid.org/0000-0002-6477-9784)
- Rainer A. Leitgeb (ORCID: https://orcid.org/0000-0002-0131-4111)
- Xinyu Liu (ORCID: https://orcid.org/0009-0008-8239-6294)
Institutions
- National University of Singapore (SG)
- Singapore National Eye Center (SG)
- Singapore Eye Research Institute (SG)
- Duke-NUS Medical School (SG)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1117/1.jbo.29.12.126001
- Citations
- 1
- Primary Topic
- Optical Coherence Tomography Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.18
Funders
- Lee Foundation
- Duke-NUS Medical School
- National Research Foundation
- National Research Foundation Singapore
- Singapore Eye Research Institute
- Nanyang Technological University
- Medical Research Council
- National Medical Research Council