Bullous Pemphigoid Onset Following Vaccination in Infancy: A Case Report

Bullous pemphigoid (BP) is a rare autoimmune blistering disease characterised by autoantibodies against basal skin membrane antigens. Although the condition's aetiology remains unclear, recent cases have raised suspicions of an association with immunisation. In this study, we present a case of BP onset in a four-month-old infant following routine vaccination. The infant with BP responded well to systemic therapy. This case emphasises the requirement for further investigation into the potential link between BP and vaccination.

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Journal
Cureus
Published
2024-12-19
DOI
https://doi.org/10.7759/cureus.76017
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
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0.00
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article

Bullous Pemphigoid Onset Following Vaccination in Infancy: A Case Report

Nicola Hardcastle, Arnav Katira, Sondos Hassanin
1 links
Cureus
Autoimmune Bullous Skin Diseases
article

Bullous Pemphigoid Onset Following Vaccination in Infancy: A Case Report

Nicola Hardcastle, Arnav Katira, Sondos Hassanin
article en

Abstract

Bullous pemphigoid (BP) is a rare autoimmune blistering disease characterised by autoantibodies against basal skin membrane antigens. Although the condition's aetiology remains unclear, recent cases have raised suspicions of an association with immunisation. In this study, we present a case of BP onset in a four-month-old infant following routine vaccination. The infant with BP responded well to systemic therapy. This case emphasises the requirement for further investigation into the potential link between BP and vaccination.

CureusVol. 16(12)
Sheffield Children's Hospital (GB)
Openalex Percentile: Top 62%
Autoimmune Bullous Skin Diseases
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