Efficacy and safety of evenamide, a glutamate modulator, added to a second-generation antipsychotic in inadequately/poorly responding patients with chronic schizophrenia: Results from a randomized, double-blind, placebo-controlled, phase 3, internati

The demonstration of statistically significant and clinically meaningful benefit of evenamide, a glutamate modulator, as add-on treatment in patients with chronic schizophrenia inadequately responding to their second-generation antipsychotic may represent a new treatment paradigm for this population.

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Publication Details

Journal
Neuropharmacology
Published
2024-12-19
DOI
https://doi.org/10.1016/j.neuropharm.2024.110275
Citations
10
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
3.86
Controls
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article

Efficacy and safety of evenamide, a glutamate modulator, added to a second-generation antipsychotic in inadequately/poorly responding patients with chronic schizophrenia: Results from a randomized, double-blind, placebo-controlled, phase 3, internati

Richard D. Hartman, Alessio Turolla, Arjun Roy, Ravi Anand et al.
10 citations
Neuropharmacology
Schizophrenia research and treatment
3.86
article

Efficacy and safety of evenamide, a glutamate modulator, added to a second-generation antipsychotic in inadequately/poorly responding patients with chronic schizophrenia: Results from a randomized, double-blind, placebo-controlled, phase 3, internati

Richard D. Hartman, Alessio Turolla, Arjun Roy, Ravi Anand, Giovanni Chinellato, F. Sansi
article en
10 citations

Abstract

The demonstration of statistically significant and clinically meaningful benefit of evenamide, a glutamate modulator, as add-on treatment in patients with chronic schizophrenia inadequately responding to their second-generation antipsychotic may represent a new treatment paradigm for this population.

NeuropharmacologyVol. 266
CliniRx (India) (IN), Applied Pharma Research (Switzerland) (CH), Newron Pharmaceuticals (Italy) (IT)
Good health and well-being
Openalex Percentile: Top 5%
Schizophrenia research and treatment
3.86
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Efficacy and safety of evenamide, a glutamate modulator, added to a second-generation antipsychotic in inadequately/poorly responding patients with chronic schizophrenia: Results from a randomized, double-blind, placebo-controlled, phase 3, internati — Richard D. Hartman, Alessio Turolla, et al. · Neuropharmacology (2024) | TGRS Research Map | TGRS