PF4 Silencing Promotes Trophoblast Cell Proliferation, Migration, Invasion and EMT by Regulating SOCS3/STAT3 Signaling Pathway

In summary, PF4 participated in the proliferation, migration, invasion, EMT and angiogenesis of trophoblast cells by modulating the SOCS3/STAT3 signaling pathway, indicating that targeting the PF4/SOCS3/STAT3 pathway could be a novel therapy for RM.

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Publication Details

Journal
Endocrine Metabolic & Immune Disorders - Drug Targets
Published
2024-12-17
DOI
https://doi.org/10.2174/0118715303299470240723060939
Citations
3
Primary Topic
Reproductive System and Pregnancy
Type
article
Field-Weighted Citation Impact
0.72
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article

PF4 Silencing Promotes Trophoblast Cell Proliferation, Migration, Invasion and EMT by Regulating SOCS3/STAT3 Signaling Pathway

Hui Cao, Guantai Ni, Ling Li, Ranran Li
3 citations
Endocrine Metabolic & Immune Disorders - Drug Targets
Reproductive System and Pregnancy
0.72
article

PF4 Silencing Promotes Trophoblast Cell Proliferation, Migration, Invasion and EMT by Regulating SOCS3/STAT3 Signaling Pathway

Hui Cao, Guantai Ni, Ling Li, Ranran Li
article en
3 citations

Abstract

In summary, PF4 participated in the proliferation, migration, invasion, EMT and angiogenesis of trophoblast cells by modulating the SOCS3/STAT3 signaling pathway, indicating that targeting the PF4/SOCS3/STAT3 pathway could be a novel therapy for RM.

Endocrine Metabolic & Immune Disorders - Drug TargetsVol. 25
Anhui Medical University (CN), First Affiliated Hospital of Wannan Medical College (CN)
Openalex Percentile: Top 27%
Reproductive System and Pregnancy
0.72
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PF4 Silencing Promotes Trophoblast Cell Proliferation, Migration, Invasion and EMT by Regulating SOCS3/STAT3 Signaling Pathway — Hui Cao, Guantai Ni, et al. · Endocrine Metabolic & Immune Disorders - Drug Targets (2024) | TGRS Research Map | TGRS