Anti-VSMC Vegetation Activities of New Aurone Various Synthetic Methods and Biological Potentials of Aurone Analogs

The aurone derivatives are a subfamily of flavonoids. Aurones can be easily broken down into two major parts, a benzofuranone and an exocyclic arylidene, often made from an aldehyde, despite having the normal 15-carbon structure. However, aurone derivatives have recently received considerable attention due to their diverse biological effects. These derivatives are synthesized by different chemical methods and exhibit different types of biological actions such as antibacterial, antiviral, antimalarial, anticancer, antiplasmodial, antiparasitic, anti-inflammatory, antioxidant, and other beneficial biological activities. Furoaurone (a semi-synthetic compound), also known as benzofuran-3(2H)-one, is made from naturally occurring furanochromones collected from Ammivisnaga fruits. In this review, we study the numerous synthetic techniques for aurone and furanone derivatives and various biological functions.