Phenotypic characterization of NK cells in 5-year-old children exposed to maternal HIV and antiretroviral therapy in early-life
The proportions of total NK cell, CD56<sup>bright</sup> and CD56<sup>dim</sup> NK cells, NK cells inhibitory and differentiation surface marker expression and cytolytic granule-positive cells were similar between HEU and HUU children. These data suggest that early-life HIV/ART exposure may not result in major changes in NK cell subsets at 5 years of age.
Authors
- Ana Jordan-Paiz (ORCID: https://orcid.org/0000-0002-3495-7201)
- Kerina Duri (ORCID: https://orcid.org/0000-0003-2692-5290)
- Hope Mataramvura
- Julia Jäger
- Lovemore Ronald Mazengera
- Madeleine J. Bunders (ORCID: https://orcid.org/0000-0002-9538-9500)
- Felicity Zvanyadza Gumbo
Institutions
- Leibniz Institute of Virology (LIV) (DE)
- University of Zimbabwe (ZW)
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
Publication Details
- Journal
- BMC Immunology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12865-024-00674-4
- Citations
- 4
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Wellcome Trust
- Deutsche Forschungsgemeinschaft
- Leibniz-Gemeinschaft