Neutrophil extracellular traps and oxidative stress in systemic lupus erythematosus patients with and without renal involvement
Levels of NETs were increased in quiescent SLE patients. Although free thiol levels did not differ among the groups. The levels of NETs and free thiols were independently associated in SLE patients, suggesting a potential role of OS in NETs formation. Therefore, reducing OS might be an additional therapeutic target for SLE treatment.
Authors
- Harry van Goor (ORCID: https://orcid.org/0000-0002-6670-1577)
- Johanna Westra (ORCID: https://orcid.org/0000-0002-6581-6508)
- Karina de Leeuw (ORCID: https://orcid.org/0000-0003-0218-9364)
- Suzanne Arends (ORCID: https://orcid.org/0000-0002-4422-7640)
- Berber Doornbos‐van der Meer
- Lu Liu (ORCID: https://orcid.org/0000-0001-9274-1372)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13075-024-03454-y
- Citations
- 6
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- China Scholarship Council