Melioidosis in goats at a single Australian farm was caused by multiple diverse lineages of Burkholderia pseudomallei present in soil
Agricultural animals can influence B. pseudomallei abundance and diversity in local environments. This effect may persist, as B. pseudomallei was detected more often from soil collected inside and adjacent to goat enclosures years after most goats were removed. Following goat removal, the low virulence ST326, which was not isolated from soil when goats were present, became the predominant ST in soil by 2006. Although multiple diverse lineages of B. pseudomallei may exist in a given location, some may infect mammals more efficiently than others.
Authors
- Richard A. Bowen (ORCID: https://orcid.org/0000-0002-7576-2881)
- Mark Mayo (ORCID: https://orcid.org/0000-0002-9413-0142)
- Mirjam Kaestli (ORCID: https://orcid.org/0000-0002-6053-5141)
- Adam J. Vazquez (ORCID: https://orcid.org/0000-0001-8625-3436)
- Apichai Tuanyok (ORCID: https://orcid.org/0000-0002-3380-0448)
- Glenda Harrington
- Joseph D. Busch (ORCID: https://orcid.org/0000-0003-4775-8225)
- Jodie Low Choy
- Paul Keim (ORCID: https://orcid.org/0000-0003-0089-5820)
- Chandler C. Roe (ORCID: https://orcid.org/0000-0002-5762-7846)
- Nathan E. Stone (ORCID: https://orcid.org/0000-0002-8723-359X)
- Bart J. Currie (ORCID: https://orcid.org/0000-0002-8878-8837)
- Jason W. Sahl (ORCID: https://orcid.org/0000-0002-2497-0138)
- Christopher J. Allender (ORCID: https://orcid.org/0000-0002-6808-7611)
- David M. Wagner (ORCID: https://orcid.org/0000-0003-2684-6007)
- Suresh Benedict
Institutions
- Northern Arizona University (US)
- Charles Darwin University (AU)
- University of Florida (US)
- Menzies School of Health Research (AU)
- Colorado State University (US)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1371/journal.pntd.0012683
- Primary Topic
- Burkholderia infections and melioidosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- National Institutes of Health