Impact of Cefotaxime on Hepatic Enzymes and Some Laboratory Parameters

This study investigates the impact of Cefotaxime, Cefotaxime is a third-generation cephalosporin antibiotic that is commonly used to treat a variety of bacterial infections. It is generally well-tolerated. In this study, we investigated the impact of cefotaxime on hepatic enzymes and some laboratory parameters in patients with bacterial infections. The homogeneity of the sample across age, weight, and length variables is established through the analysis of arithmetic mean, standard deviation, and coefficient of variation. Results indicate a low coefficient of variation, signifying accurate and homogeneous data. The result illustrates a 1% decrease in hemoglobin levels after Cefotaxime administration. The study attributes this effect to decrease red blood , in blood cell count, emphasizing Cefotaxime's efficacy in increasing WBCs, crucial for infection defense. Presents mean and standard deviation values for hemoglobin, WBC, S.GOT, S.ALT, S.ALP, S.Na, and S.K before and after Cefotaxime. The significant decrease in hemoglobin levels and rise in WBC count after Cefotaxime administration is evident, with a calculated T-value indicating high significance. Cefotaxime exhibits a notable impact on hematological and biochemical parameters, emphasizing its influence on hemoglobin and white blood cell levels. The study contributes valuable insights into the potential effects of Cefotaxime on hepatic enzymes and laboratory markers, enhancing our understanding of its clinical implications.