Impact of Immobilization Method on DNA Stretching Characteristics
The problem of stretching a flexible polymer with given conditions at the ends, under the action of a fixed force, is considered. A mathematical model is constructed for different energy functions describing the elasticity of the polymer and different immobilization methods. It is shown that the dependence of stretching on the polymer length is linear. Numerical results are given. The results obtained allow to improve the analysis of experimental data on polymer stretching. The theory offers several verifiable predictions, and experimental methods are proposed to improve the accuracy of measurements.
Authors
- M. A. Didin
Institutions
- Moscow Institute of Physics and Technology (RU)
Publication Details
- Journal
- Биофизика
- Published
- 2024-12-15
- DOI
- https://doi.org/10.31857/s0006302924060021
- Primary Topic
- DNA and Nucleic Acid Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00