Cell-Free DNA Analysis of Fetal Aneuploidies in Early Pregnancy Loss
(Abstracted from J Clin Med 2024;13(15):4283 Approximately 10% to 20% of pregnancies end in miscarriage, or early pregnancy loss (EPL), with most losses occurring in the first trimester. An estimated half of EPLs are due to chromosomal abnormalities, including trisomies, monosomies, and sex chromosome abnormalities, with another 10% due to polyploidy, uniparental disomy, and copy-number variants.
Authors
- Damian P. Alagia
- Mauro Chavez (ORCID: https://orcid.org/0000-0001-9126-8608)
- Kristine N. Jinnett
- Charles E. Miller (ORCID: https://orcid.org/0000-0002-1892-2818)
- Victoria Corey
- Kirsten J. Curnow (ORCID: https://orcid.org/0000-0001-8364-6429)
- William H. Kutteh (ORCID: https://orcid.org/0000-0002-6049-3842)
- Karen Racicot (ORCID: https://orcid.org/0000-0002-2887-2543)
- John K. Park
- David L. Keefe (ORCID: https://orcid.org/0000-0001-6704-6343)
- Sucheta Bhatt
- Kristin Dalton
Publication Details
- Journal
- Obstetrical & Gynecological Survey
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1097/ogx.0000000000001355
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00