Valproate Use During Spermatogenesis and Risk to Offspring
(Abstracted from JAMA Network Open 2024;7(6):e2414709 Valproate, an antiseizure medication, is correlated with increased risk of congenital malformations and neurodevelopmental disorders, including autism, in children when taken by pregnant women. Because valproate is commonly prescribed to epileptic men of fertile age, concerns have been raised about its potential effects on spermatogenesis.
Authors
- Julie Werenberg Dreier (ORCID: https://orcid.org/0000-0002-9339-4170)
- Jakob Munkholt Christensen (ORCID: https://orcid.org/0000-0002-2495-8905)
- Betina B. Trabjerg (ORCID: https://orcid.org/0000-0001-6282-2614)
Publication Details
- Journal
- Obstetrical & Gynecological Survey
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1097/ogx.0000000000001352
- Citations
- 1
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.11