Quantitative 18F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis
<sup>18</sup>F-FDG PET-CT can detect metabolic activity in the lungs of patients with early severe diffuse cutaneous SSc and ILD, correlating with higher ILD extent (≥ 20%) and lower DLCO%. These results suggest the potential utility of <sup>18</sup>F-FDG PET-CT in the early detection of ILD (progression) and aiding in risk stratification.
Authors
- Jeska K de Vries‐Bouwstra (ORCID: https://orcid.org/0000-0002-5624-1415)
- Bo Broens
- Esther J. Nossent (ORCID: https://orcid.org/0000-0003-3854-4137)
- Alexandre E. Voskuyl (ORCID: https://orcid.org/0000-0002-9699-1827)
- Jacob M. van Laar (ORCID: https://orcid.org/0000-0001-5544-5785)
- Julia Spierings (ORCID: https://orcid.org/0000-0002-2546-312X)
- Gerben J.C. Zwezerijnen (ORCID: https://orcid.org/0000-0002-9571-9362)
- Lilian J. Meijboom (ORCID: https://orcid.org/0000-0002-7528-8307)
- Conny J. van der Laken (ORCID: https://orcid.org/0000-0002-9865-6213)
Institutions
- Leiden University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13075-024-03447-x
- Citations
- 9
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.82
Funders
- Dutch Arthritis Society
- Arthritis Society
- ZonMw