Hemoglobin A1c and abdominal obesity as predictors of diabetes and ASCVD in individuals with prediabetes in UK Biobank: a prospective observational study
The risks of progression to both new onset DM and ASCVD are significantly greater in the prediabetic population. This underscores the importance of preventing the development of DM and efforts to reduce cardiometabolic risk through optimizing multiple risk factors in both categories of prediabetes. Risk modification by waist circumference suggests weight and glucose lowering therapies should be targeted at those with highest risks.
Authors
- Karol M. Pencina (ORCID: https://orcid.org/0000-0003-1824-7047)
- Allan D. Sniderman (ORCID: https://orcid.org/0000-0002-3540-3956)
- George Thanassoulis (ORCID: https://orcid.org/0000-0002-9930-7189)
- Peter P. Tóth (ORCID: https://orcid.org/0000-0001-5810-5460)
- Michael Pencina (ORCID: https://orcid.org/0000-0002-1968-2641)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Duke University (US)
- Royal Victoria Regional Health Centre (CA)
- Johns Hopkins Medicine (US)
- McGill University Health Centre (CA)
- Royal Victoria Hospital (CA)
- CGH Medical Center (US)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s12933-024-02525-3
- Citations
- 5
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.79