Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism
Dietary sodium restriction in patients with PA modulates the peripheral immune cell composition toward a less inflammatory phenotype. This suggests a potential mechanism by which sodium reduction modulates immune cell composition, leading to blood pressure reduction and positively impacting cardiovascular risk.
Authors
- Anne L. Potzel (ORCID: https://orcid.org/0000-0003-1900-9462)
- Holger Schneider (ORCID: https://orcid.org/0000-0002-8798-2961)
- Christian Adolf
- Thomas Marchant Seiter
- Martín Reincke (ORCID: https://orcid.org/0000-0002-9817-9875)
- Andreas Lechner (ORCID: https://orcid.org/0000-0002-0276-291X)
- H. Nowotny (ORCID: https://orcid.org/0000-0003-3791-9929)
- Sonja Kunz
- Anna‐Lina Sarkis
- Adrian Gottschlich (ORCID: https://orcid.org/0000-0002-2898-4182)
- Klaus Neuhaus (ORCID: https://orcid.org/0000-0002-6020-2814)
- Matthias Kroiß (ORCID: https://orcid.org/0000-0002-7628-3161)
- Sebastian Kobold (ORCID: https://orcid.org/0000-0002-5612-4673)
- Nicole Reisch (ORCID: https://orcid.org/0000-0002-7469-6069)
- Martin Bidlingmaier (ORCID: https://orcid.org/0000-0002-4681-6668)
- Vera Britz
- Melanie Schirmer (ORCID: https://orcid.org/0000-0001-6456-3679)
- Tingting Zheng (ORCID: https://orcid.org/0000-0002-2782-2800)
- Jing Ju (ORCID: https://orcid.org/0000-0002-1901-6980)
- Lisa Sturm (ORCID: https://orcid.org/0000-0002-5771-8748)
Institutions
- German Cancer Research Center (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- Leibniz-Institute for Food Systems Biology at the Technical University of Munich (DE)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Heinrich Heine University Düsseldorf (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.3389/fimmu.2024.1428054
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Melanoma Research Alliance
- European Commission
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- Bayerische Forschungsstiftung
- Else Kröner-Fresenius-Stiftung
- Ludwig-Maximilians-Universität München
- Deutsche Krebshilfe
- Hector Stiftung
- Elitenetzwerk Bayern