Intravenous Lipid Emulsion for Managing Local Anesthetic Toxicity in a Three-Month-Old Patient

Local anesthetic systemic toxicity (LAST) is a well-known life-threatening local anesthetics complication, especially if given in inappropriate doses or routes. Therefore, physicians should be aware of LAST symptoms, such as neurological and cardiac symptoms. In addition, they should always consider it in the differential diagnosis when they encounter similar symptoms. The early recognition of LAST and initiation of intravenous lipid emulsion (ILE) can decrease mortality and morbidity rates. Multiple organizations and guidelines use ILE as standard LAST management. We present a three-month-old infant who received a caudal block that was complicated by an inadvertent intravascular injection that led to LAST cardiac symptoms. ILE successfully managed these symptoms, and the patient returned to normal vital signs without any complications.

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Publication Details

Journal
Cureus
Published
2024-12-18
DOI
https://doi.org/10.7759/cureus.75981
Primary Topic
Anesthesia and Pain Management
Type
article
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article

Intravenous Lipid Emulsion for Managing Local Anesthetic Toxicity in a Three-Month-Old Patient

Abdullah A. B. Bokhari, Abdulrahman S Alquzi, Bader Alsabban
Cureus
Anesthesia and Pain Management
article

Intravenous Lipid Emulsion for Managing Local Anesthetic Toxicity in a Three-Month-Old Patient

Abdullah A. B. Bokhari, Abdulrahman S Alquzi, Bader Alsabban
article en

Abstract

Local anesthetic systemic toxicity (LAST) is a well-known life-threatening local anesthetics complication, especially if given in inappropriate doses or routes. Therefore, physicians should be aware of LAST symptoms, such as neurological and cardiac symptoms. In addition, they should always consider it in the differential diagnosis when they encounter similar symptoms. The early recognition of LAST and initiation of intravenous lipid emulsion (ILE) can decrease mortality and morbidity rates. Multiple organizations and guidelines use ILE as standard LAST management. We present a three-month-old infant who received a caudal block that was complicated by an inadvertent intravascular injection that led to LAST cardiac symptoms. ILE successfully managed these symptoms, and the patient returned to normal vital signs without any complications.

CureusVol. 16(12)
King Abdulaziz Medical City (SA)
Openalex Percentile: Top 56%
Anesthesia and Pain Management
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