Sacubitril/Valsartan Preserves Regional Cardiac Function Following Myocardial Infarction in Rats
Sac/Val preserves in vivo myocardial function in the region most proximal to MI in rats and reduces left ventricular dilatation. These effects may be related to a reduction in both fibrosis and pro-apoptotic signalling.
Authors
- Kaja Knudsen Bergo (ORCID: https://orcid.org/0000-0002-3322-0929)
- Rizwan I. Hussain
- Ida Marie Hauge‐Iversen (ORCID: https://orcid.org/0000-0002-2839-1061)
- Michael Frisk (ORCID: https://orcid.org/0000-0001-9430-7908)
- William E. Louch (ORCID: https://orcid.org/0000-0002-0511-6112)
- Almira Hasic
- Nishani S. Mabotuwana
- Emil Knut Stenersen Espe (ORCID: https://orcid.org/0000-0001-8500-4921)
- Alessandro Cataliotti (ORCID: https://orcid.org/0000-0001-5476-8523)
- Xin Shen (ORCID: https://orcid.org/0000-0003-4429-8358)
- Ivar Sjaastad (ORCID: https://orcid.org/0000-0002-0131-2036)
- Geir Christensen (ORCID: https://orcid.org/0000-0002-7530-0767)
- Bård Andre Bendiksen (ORCID: https://orcid.org/0000-0002-2010-4881)
- Gary McGinley
- Einar Sjaastad Nordén
- Lili Zhang (ORCID: https://orcid.org/0000-0002-8211-0208)
- Hege Katrin Ugland
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Alfsen og Gunderson (Norway) (NO)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2024-12-18
- DOI
- https://doi.org/10.1002/ehf2.15145
- Citations
- 3
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Novartis
- Olav Raagholt og Gerd Meidel Raagholts stiftelse
- Universitetet i Oslo
- Norges Forskningsråd
- Anders Jahres Fond til Vitenskapens Fremme
- Simon Fougner Hartmanns Familiefond