Analysis of immune cell activation in patients with diabetes foot ulcer from the perspective of single cell
This study offers insights into DM and DFU cytology. T cells in DFU are activated, attacking normal tissues and worsening tissue damage. The ATP5E gene may be related to the ecological remodeling of DM, and TPP1, TLR4, and RIPK2 are potential targets for DFU treatment.
Authors
- Fei Xu (ORCID: https://orcid.org/0000-0003-1077-0431)
- Yongqiang Jiang (ORCID: https://orcid.org/0000-0001-8970-4570)
- Steven Mo (ORCID: https://orcid.org/0000-0002-4751-854X)
- Ke-Er Lu
- Kaihua Tang (ORCID: https://orcid.org/0000-0002-1008-7053)
- Lung Vu (ORCID: https://orcid.org/0000-0001-9088-7407)
- Kejian Wang (ORCID: https://orcid.org/0000-0002-8385-6714)
- Chengyu Huang (ORCID: https://orcid.org/0000-0002-6473-8800)
- Weiliang Mo
- Qikai Hua (ORCID: https://orcid.org/0000-0001-5101-6115)
- Xiaocong Kuang
- Dengfeng Yang (ORCID: https://orcid.org/0000-0003-0596-6157)
- Mo Yan (ORCID: https://orcid.org/0009-0008-4465-7342)
- Yixuan Chen (ORCID: https://orcid.org/0000-0002-4879-7165)
- Yanfei Liang
- Jin-min Zhao (ORCID: https://orcid.org/0000-0001-8917-3861)
- Jianwen Mo
- Xing Niu
- Ting Li (ORCID: https://orcid.org/0009-0003-3570-2563)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Center for Life Sciences (CN)
- Guangxi Academy of Sciences (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s40001-024-02179-7
- Citations
- 3
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China
- Guangxi Medical University
- Guangxi Key Research and Development Program