BET inhibition revealed varying MYC dependency mechanisms independent of gene alterations in aggressive B-cell lymphomas
This work brings new insights into the complexity of MYC-dependencies and unravels a novel targetable oncogenic pathway in aggressive B-cell lymphomas.
Authors
- Andrea Cecilia Garcia-Sandoval (ORCID: https://orcid.org/0000-0002-9479-5400)
- Camille Teste (ORCID: https://orcid.org/0009-0001-7637-0863)
- Émilie Montaut
- Thierry Bonnefoix (ORCID: https://orcid.org/0000-0002-7779-908X)
- Patricia Betton-Fraisse
- Christine Lefebvre (ORCID: https://orcid.org/0000-0003-0424-3731)
- Jérôme Govin (ORCID: https://orcid.org/0000-0001-5511-6965)
- Loris Delrieu
- Rémy Gressin (ORCID: https://orcid.org/0000-0002-9188-3501)
- Sylvain Carras (ORCID: https://orcid.org/0000-0002-0796-7914)
- Sieme Hamaidia (ORCID: https://orcid.org/0000-0002-9958-1399)
- Anouk Emadali (ORCID: https://orcid.org/0000-0002-1976-2668)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13148-024-01788-7
- Citations
- 2
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Infrastructures en Biologie Santé et Agronomie
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
- Université Claude Bernard Lyon 1
- École Normale Supérieure de Lyon