Comprehensive pan-cancer analysis indicates UCHL5 as a novel cancer biomarker and promotes cervical cancer progression through the Wnt signaling pathway
Pan-cancer analysis indicates that UCHL5 is dysregulated in various tumor tissues and is closely associated with survival prognosis, the tumor immune microenvironment, and the efficacy of immunotherapy in certain cancer types. UCHL5 shows promise as a predictive biomarker, and its specific regulatory mechanisms across different cancers warrant further investigation.
Authors
- Lingling Bao (ORCID: https://orcid.org/0000-0003-0891-6032)
- Kailang Li (ORCID: https://orcid.org/0000-0001-7019-4742)
- Zhongxuan Gui
- Zhengting Ren
- Xin Xu (ORCID: https://orcid.org/0000-0002-5918-863X)
- Yingquan Ye (ORCID: https://orcid.org/0000-0002-4426-2841)
- Yuefei Wu
- Yi‐Wen Huang (ORCID: https://orcid.org/0000-0002-5196-7030)
- Yue Jiang (ORCID: https://orcid.org/0009-0003-1134-5602)
Institutions
- University of Nottingham Ningbo China (CN)
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Wuhu Fourth People Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Xian Yang Central Hospital (CN)
- Ningbo No.6 Hospital (CN)
- Ningbo First Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Biology Direct
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13062-024-00588-6
- Citations
- 17
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.97
Funders
- Anhui Medical University