Biological hallmarks of systemic sclerosis are present in the skin and serum of patients with Very Early Diagnosis of Systemic Sclerosis (VEDOSS)

Despite not fulfilling classification criteria, VEDOSS patients show SSc-linked fibrosis and immunity dysregulation both within the tissue and sera, supporting a biological diagnosis of disease and a window of opportunity to detect the biological pathways amenable for preventive intervention.

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Publication Details

Journal
Lara D. Veeken
Published
2024-12-19
DOI
https://doi.org/10.1093/rheumatology/keae698
Citations
11
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
4.67

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article

Biological hallmarks of systemic sclerosis are present in the skin and serum of patients with Very Early Diagnosis of Systemic Sclerosis (VEDOSS)

Andrea Rindone, Christopher W. Wasson, Emily L. Clarke, Panji Mulipa et al.
11 citations
Lara D. Veeken
Systemic Sclerosis and Related Diseases
4.67
article

Biological hallmarks of systemic sclerosis are present in the skin and serum of patients with Very Early Diagnosis of Systemic Sclerosis (VEDOSS)

Andrea Rindone, Christopher W. Wasson, Emily L. Clarke, Panji Mulipa, Enrico De Lorenzis, Begoña Caballero-Ruiz, Ariane L. Herrick, Francesco Del Galdo, Natalia A. Riobo‐Del Galdo, Stefano Di Donato, Vishal Kakkar, Rebecca L. Ross, Christopher P. Denton, Will Merchant
article en
11 citations

Abstract

Despite not fulfilling classification criteria, VEDOSS patients show SSc-linked fibrosis and immunity dysregulation both within the tissue and sera, supporting a biological diagnosis of disease and a window of opportunity to detect the biological pathways amenable for preventive intervention.

Lara D. VeekenVol. 64(6)
Università Cattolica del Sacro Cuore (IT), University of Leeds (GB), University of Milan (IT), Chapel Allerton Hospital (GB), Leeds Teaching Hospitals NHS Trust (GB), Manchester Academic Health Science Centre (GB), St James's University Hospital (GB), Agostino Gemelli University Polyclinic (IT), University of Manchester (GB), Istituto Ortopedico Gaetano Pini (IT), NIHR Leeds Musculoskeletal Biomedical Research Unit (GB), British Society for Rheumatology (GB), University of the Sacred Heart (JP), Institute of Structural and Molecular Biology (GB), Center for Rheumatology (US), University College London (GB), Leeds Beckett University (GB)
National Institute for Health and Care Research, Department of Health and Social Care, Sight Research UK, Manchester Biomedical Research Centre, Medical Research Council, Leeds Biomedical Research Centre, Faculty of Medicine and Health, University of Sydney
Good health and well-being
Openalex Percentile: Top 5%
Systemic Sclerosis and Related Diseases
4.67
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