Actionable mutations in early-stage ovarian cancer according to the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT): a descriptive analysis on a large prospective cohort
These findings highlight the potential for actionable alterations in most early-stage EOC patients and support the exploration of chemotherapy-free regimens for low- to intermediate-risk groups, as well as targeted maintenance therapy for high-risk individuals.
Authors
- Floriana Camarda (ORCID: https://orcid.org/0000-0002-5206-6867)
- C. Marchetti
- C. Nero
- Elisa De Paolis (ORCID: https://orcid.org/0000-0002-0780-0153)
- Luca Mastrantoni (ORCID: https://orcid.org/0000-0003-1853-4927)
- Maria Rosaria Manfredelli
- Gian Franco Zannoni (ORCID: https://orcid.org/0000-0002-4473-7560)
- Tina Pasciuto (ORCID: https://orcid.org/0000-0003-2959-8571)
- Franco Persiani
- G Scambia
- Angelo Minucci (ORCID: https://orcid.org/0000-0002-0833-4334)
- Diana Giannarelli (ORCID: https://orcid.org/0000-0002-6085-1195)
- C. Parrillo
- F. Giacomini
- Anna Fagotti
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- ESMO Open
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1016/j.esmoop.2024.104090
- Citations
- 4
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.15