Evaluation of neutralizing antibody titers against SARS-CoV-2 JN.1 omicron subvariant during pregnancy - A case series study
NAb titers change dynamically during pregnancy, increasing then decreasing. Most pregnant women were asymptomatic and NAbs were effectively transferred to the fetus when infection or vaccination occurred near delivery. These findings highlight the importance of vaccination timing, suggesting late second or third trimester vaccination may provide better protection, emphasizing the need for adherence to vaccination guidelines to optimize maternal and neonatal immunity.
Authors
- Julien Favresse (ORCID: https://orcid.org/0000-0002-9805-049X)
- Constant Gillot (ORCID: https://orcid.org/0000-0002-4151-9760)
- Marie Didembourg (ORCID: https://orcid.org/0000-0002-9170-0314)
- Laure Morimont (ORCID: https://orcid.org/0000-0001-9195-304X)
- Jonathan Douxfils (ORCID: https://orcid.org/0000-0002-7644-5298)
- Clara David
- Eva Cransquint
Institutions
- University of Namur (BE)
- Comagine Health (US)
- Clinique Saint-Joseph (BE)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41249
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00