A Model-Based Evaluation of Noninvasive Biomarkers to Reflect Histological Nonalcoholic Fatty Liver Disease Scores
An in silico histological liver score model allowed to simultaneously quantitatively analyze 13 features beyond NAS and fibrosis, characterizing different disease facets underlying NAFLD and revealing the contrasting ability of 69 noninvasive biomarkers to reflect the diverse histological (sub-)scores.
Authors
- Iris K. Minichmayr (ORCID: https://orcid.org/0000-0002-2679-8589)
- Elodie L. Plan (ORCID: https://orcid.org/0000-0002-2255-3904)
- Sebastian Ueckert (ORCID: https://orcid.org/0000-0002-3712-0255)
- Benjamin Weber (ORCID: https://orcid.org/0000-0002-1316-5184)
Institutions
- Uppsala University (SE)
- Novo Nordisk (Denmark) (DK)
- Swedish University of Agricultural Sciences (SE)
- Profu (Sweden) (SE)
- Boehringer Ingelheim (United States) (US)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1007/s11095-024-03791-2
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Uppsala Universitet