Atherosclerotic plaque evolution predicts cerebral ischemic events in patients with intracranial atherosclerosis: a multicentre longitudinal study using high-resolution MRI
Question Can longitude high-resolution magnetic resonance imaging (hrMRI) help clinicians observe intracranial plaque evolution? Findings Compared with the baseline exam, intracranial plaque evolution distinguished by follow-up hrMRI exam showed a higher accuracy in predicting subsequent ischemic events. Clinical relevance Longitudinal high-resolution magnetic resonance vessel wall imaging enables dynamic observation and evaluation of the changes in plaque characteristics among intracranial atherosclerosis patients. Atherosclerotic plaque evolution revealed by repeated exams can strengthen the risk stratification of patients with intracranial atherosclerosis.
Authors
- Jinhua Shen (ORCID: https://orcid.org/0000-0001-6795-4501)
- Wusheng Zhu (ORCID: https://orcid.org/0000-0003-0668-5832)
- Weihe Yao (ORCID: https://orcid.org/0000-0001-5574-8575)
- Dahong Yang
- Wenjia Peng (ORCID: https://orcid.org/0000-0002-5543-3677)
- Kangmo Huang (ORCID: https://orcid.org/0000-0003-1354-5459)
- Xiaoqing Cheng (ORCID: https://orcid.org/0000-0001-5321-1459)
- Zhongzhao Teng (ORCID: https://orcid.org/0000-0003-3973-6157)
- Hongbing Chen (ORCID: https://orcid.org/0000-0002-4845-383X)
- Xinfeng Liu (ORCID: https://orcid.org/0000-0002-8182-9632)
- Juan Du (ORCID: https://orcid.org/0000-0001-5083-9435)
- Yunfei Han
- Jialuo Yang
- Xuefeng Zhang (ORCID: https://orcid.org/0009-0005-7008-4363)
- Junjun Wang (ORCID: https://orcid.org/0009-0009-7427-8690)
Institutions
- Sun Yat-sen University (CN)
- Second Military Medical University (CN)
- University of Cambridge (GB)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Changhai Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- European Radiology
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1007/s00330-024-11248-8
- Citations
- 6
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- National Institute for Health and Care Research
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality
- NIHR Cambridge Biomedical Research Centre