Studying the characteristics of bovine foamy virus at the cultural and molecular genetic level

The article is devoted to the study of the adaptive capacity of bovine foamy virus to homologous continuous cell cultures, namely LEK and KST. In the process of integration of the causative agent of spumavirus infection in cattle into the continuous cultures LEK and KST, morphological changes in the state of the monolayer are observed on the principle of syncytium formation and vacuolization. It was found that LEK continuous cell culture is more suitable for pathogen replication and accumulation of viral mass. Studies on the possibility of integrating the field form of bovine foamy virus into the continuous cell culture KST showed low sensitivity of the latter to the virus of the Retroviridae family

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Journal
Veterinary Medicine inter-departmental subject scientific collection
Published
2024-10-23
DOI
https://doi.org/10.36016/vm-2024-110-11
Primary Topic
Animal Disease Management and Epidemiology
Type
article
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article

Studying the characteristics of bovine foamy virus at the cultural and molecular genetic level

О. V. Kuznetsova, O. V. Dunaeva, T. B. Didyk, O. B. Kornieikova et al.
Veterinary Medicine inter-departmental subject scientific collection
Animal Disease Management and Epidemiology
article

Studying the characteristics of bovine foamy virus at the cultural and molecular genetic level

О. V. Kuznetsova, O. V. Dunaeva, T. B. Didyk, O. B. Kornieikova, S. K. Gorbatenko, N. F. Bryl, N. V. Myagkikh
article en

Abstract

The article is devoted to the study of the adaptive capacity of bovine foamy virus to homologous continuous cell cultures, namely LEK and KST. In the process of integration of the causative agent of spumavirus infection in cattle into the continuous cultures LEK and KST, morphological changes in the state of the monolayer are observed on the principle of syncytium formation and vacuolization. It was found that LEK continuous cell culture is more suitable for pathogen replication and accumulation of viral mass. Studies on the possibility of integrating the field form of bovine foamy virus into the continuous cell culture KST showed low sensitivity of the latter to the virus of the Retroviridae family

Veterinary Medicine inter-departmental subject scientific collection(110)
National Scientific Center "Institute of Experimental and Clinical Veterinary Medicine" (UA), Kharkiv National Medical University (UA)
Openalex Percentile: Top 67%
Animal Disease Management and Epidemiology
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