Characterization of Cardiac Troponin Fragment Composition Reveals Potential for Differentiating Etiologies of Myocardial Injury
Kinetic differences in multiple cTn forms contribute to the differentiation between acute injury and chronic disease, with a high proportion of long-cTnT ITC complex implying occurrence of acute injury.
Authors
- Yu Wu (ORCID: https://orcid.org/0000-0001-8055-8327)
- Litao Zhang (ORCID: https://orcid.org/0000-0003-4918-611X)
- A. Bereznikova (ORCID: https://orcid.org/0000-0002-6788-693X)
- Zhenlu Zhang (ORCID: https://orcid.org/0000-0002-1999-6536)
- Tongxin Ni
- Ivan A. Katrukha (ORCID: https://orcid.org/0000-0002-5939-6201)
- Fred S. Apple (ORCID: https://orcid.org/0000-0002-5920-6498)
- Ling Li (ORCID: https://orcid.org/0009-0001-1643-0633)
- Hui Wang (ORCID: https://orcid.org/0000-0002-8549-3398)
- Yi Zhang (ORCID: https://orcid.org/0000-0001-7338-8825)
- Juan Yang (ORCID: https://orcid.org/0000-0002-0739-6998)
- Yuqing Liu (ORCID: https://orcid.org/0000-0002-7566-8529)
- Karen Schulz (ORCID: https://orcid.org/0000-0002-2725-5623)
- Xin Shu
- Yisha Jing
- Xu Ao
- Alexey G Katrukha
Institutions
- University of Minnesota (US)
- Lomonosov Moscow State University (RU)
- Hennepin County Medical Center (US)
- Wuhan University (CN)
- HyTest (Finland) (FI)
- Wuhan Asia Heart Hospital (CN)
- Moscow State University (TJ)
- Wuhan General Hospital of Guangzhou (CN)
- Hennepin Healthcare Research Institute (US)
- Mindray (China) (CN)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2024-12-17
- DOI
- https://doi.org/10.1093/clinchem/hvae200
- Citations
- 15
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 6.03
Funders
- Science, Technology and Innovation Commission of Shenzhen Municipality