SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 Axis
The tumorigenic role of SNAI1 through the PIK3R2/p-EphA2 axis was preliminarily validated in TETs. A potential therapeutic strategy for TETs may involve the inhibition of SNAI1.
Authors
- Deping Zhao (ORCID: https://orcid.org/0000-0003-0109-5171)
- Heyong Wang (ORCID: https://orcid.org/0000-0003-3024-9838)
- E Haoran
- Juemin Yu
- Chang Chen (ORCID: https://orcid.org/0000-0003-2841-1250)
- Tao Wang (ORCID: https://orcid.org/0000-0002-8895-9974)
- Lei Zhang (ORCID: https://orcid.org/0000-0003-3062-2444)
- Zhenhua Yang (ORCID: https://orcid.org/0000-0001-5802-6439)
- Long Xu (ORCID: https://orcid.org/0000-0001-8983-2687)
- Shihua Zhao (ORCID: https://orcid.org/0000-0003-1339-7476)
- Lang Xia (ORCID: https://orcid.org/0000-0003-2015-6072)
- Junqi Wu (ORCID: https://orcid.org/0000-0001-6560-3281)
- Yunlang She (ORCID: https://orcid.org/0000-0001-7854-9149)
- Junhong Guo (ORCID: https://orcid.org/0000-0002-1297-4414)
Institutions
- Tongji University (CN)
- Ningbo No. 2 Hospital (CN)
- Shanghai Pulmonary Hospital (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13046-024-03243-0
- Citations
- 4
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- Shanghai Hospital Development Center