Cumulative anticholinergic exposure and white matter hyperintensity burden in community‐dwelling older adults
The highest anticholinergic exposure was associated with greater WMH burden. Future studies should focus on longitudinal changes of WMH burden to better understand the biological mechanisms underlying the link between anticholinergics and dementia risk.
Authors
- Jalal B. Andre (ORCID: https://orcid.org/0000-0002-0896-183X)
- Chloe Krakauer (ORCID: https://orcid.org/0000-0001-7341-7630)
- Patti Curl
- Esther L. Yuh (ORCID: https://orcid.org/0000-0002-1180-2274)
- Paul K. Crane (ORCID: https://orcid.org/0000-0002-7327-3873)
- Shelly L. Gray (ORCID: https://orcid.org/0000-0001-5507-1859)
- Mahmud Mossa‐Basha (ORCID: https://orcid.org/0000-0001-7798-8158)
- Kevin Li (ORCID: https://orcid.org/0000-0003-0425-2363)
- James D. Ralston (ORCID: https://orcid.org/0000-0003-0014-2212)
- Jennifer C. Nelson (ORCID: https://orcid.org/0000-0002-2968-2661)
- Christine L. Mac Donald
Institutions
- Kaiser Permanente Washington Health Research Institute (US)
- University of California, San Francisco (US)
- University of Washington (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1111/jgs.19325
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Institute on Aging