Characterization and Safety Assessment of a Novel Antioxidant Excipient from Sustainable Recovery of Grape Processing Waste Bentonite Designed to Develop a Thermosensitive Buccal Spray for Oral Cavity Wellness
BB is confirmed as a valuable source of polyphenols, and PEG200 represents an effective extraction solvent leading to a novel functional liquid excipient characterized by an OECD-compliant variegate pool of phenols. The buccal spray then proposed represents a valuable, friendly solution for daily oral care, as it is simple to use, as well as the in vitro and ex vivo tests carried out suggested its effectiveness.
Authors
- Elena Belfiore (ORCID: https://orcid.org/0000-0002-7813-512X)
- Claudia La Mantia (ORCID: https://orcid.org/0000-0002-6570-889X)
- Giulia Di Prima (ORCID: https://orcid.org/0000-0002-3240-2704)
- Giuseppe Avellone (ORCID: https://orcid.org/0000-0002-4539-6059)
- Serena Indelicato (ORCID: https://orcid.org/0000-0001-9965-3818)
- Viviana De (ORCID: https://orcid.org/0000-0002-5186-1244)
Institutions
- University of Palermo (IT)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-12-19
- DOI
- https://doi.org/10.3390/pharmaceutics16121612
- Citations
- 3
- Primary Topic
- Phytochemicals and Antioxidant Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Università degli Studi di Palermo
- Ministero dell'Università e della Ricerca