The alternatively spliced diacylglycerol kinase gamma-Δ exon13 transcript generated under hypoxia promotes glioblastoma progression
Our study found that hypoxia-induced alternative splicing transcript DGKG-Δ exon13 promotes GBM proliferation and infiltration, which might provide a new potential target for the clinical treatment and diagnosis of GBM.
Authors
- Ming Yang (ORCID: https://orcid.org/0000-0002-8679-9137)
- Shukai Lin
- Kaya Xu (ORCID: https://orcid.org/0000-0002-5649-9678)
- Huizhi Peng (ORCID: https://orcid.org/0000-0001-9148-9283)
- Liangzhao Chu (ORCID: https://orcid.org/0000-0002-1861-2473)
- Niya Long (ORCID: https://orcid.org/0000-0001-8277-5544)
- Jian Liu (ORCID: https://orcid.org/0000-0001-5904-6415)
- Feng Han (ORCID: https://orcid.org/0000-0003-0985-980X)
- Hua Yang (ORCID: https://orcid.org/0000-0002-3624-175X)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Sanya Central Hospital (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2024-12-19
- DOI
- https://doi.org/10.32604/or.2024.055102
- Citations
- 4
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14