Effect of Low-Intensity Electromagnetic Radiation of Ultrahigh Frequency on Stress-Induced Changes in Hematological Parameters of Rats

This work investigated the effect of low-intensity electromagnetic radiation of extremely high frequency (EMR EHF) on stress-induced changes in hematological parameters in rats. The isolated action of stress factors of varying intensity was shown to significantly change a number of hematological parameters of male rats, while their combined action with EMR EHF modifies the effects of isolated stress factors. Thus, under the conditions of hypokinetic stress (HS) relative to the control, the number of erythrocytes increased by 12.7% (p<0.05); under oxidative stress (OS), hematocrit values decreased by 19.0% (p<0.001); and under acute stress, the mean concentration of hemoglobin in erythrocytes increased by 22.6% (p<0.05). The effect of stress factors of various origins in combination with EMR EHF significantly changed the effects characteristic of isolated action of these stress factors. Thus, hypokinetic stress in combination with low-intensity electromagnetic radiation of extremely high frequency (HS-EHF) compared to HS reduced the number of erythrocytes by 11.0% (p<0.05) and the hemoglobin level by 11.2% (p<0.001), restoring these indices to the control level. The combined effect of OS-EHF neutralized the effect of hematocrit reduction in OS, although reducing the mean corpuscular volume and increased the mean corpuscular hemoglobin concentration by 24.3% (p<0.001) compared to the control. The number of leukocytes and lymphocytes decreased in OS and OS-EHF, while the combination of OS with EMR EHF weakened the stress-related damaging effect of OS.