Ball-milling and piezoelectric materials enabled radical trifluoromethylation of enamides and acrylamides
A sustainable solid-state direct radical C(sp 2 )–H trifluoromethylation of enamide derivatives was developed by merging ball-milling with a stoichiometric amount of piezoelectric materials. Acrylamide were suitable substrates in this transformation.
Authors
- Thomas Castanheiro (ORCID: https://orcid.org/0000-0002-0237-3551)
- Philippe Jubault (ORCID: https://orcid.org/0000-0002-3295-9326)
- Vitalii Solomin
- Matthias Liard
Institutions
- Centre National de la Recherche Scientifique (FR)
- Normandie Université (FR)
- Université de Rouen Normandie (FR)
- Institut National des Sciences Appliquées Rouen Normandie (FR)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1039/d4qo01911c
- Citations
- 12
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 2.50