<scp>STING</scp> Activation in Macrophages and Microglia Drives Poststroke Inflammation: Implications for Neuroinflammatory Mechanisms and Therapeutic Interventions
These findings elucidated the critical role of STING-mediated type I interferon signaling in driving post-stroke neuroinflammation and underscored the potential of STING inhibition as a therapeutic strategy for alleviating neuroinflammatory responses following stroke.
Authors
- Zhiruo Liu (ORCID: https://orcid.org/0000-0003-3696-5560)
- Mengyan Hu (ORCID: https://orcid.org/0000-0002-3501-028X)
- Zhengqi Lu (ORCID: https://orcid.org/0000-0002-2118-0368)
- Wei Cai (ORCID: https://orcid.org/0000-0003-4059-4627)
- Shisi Wang (ORCID: https://orcid.org/0000-0002-6484-7169)
- Yuxin Liu
- Qin Qin (ORCID: https://orcid.org/0000-0003-2561-5709)
- Xinmei Kang (ORCID: https://orcid.org/0000-0002-3039-5221)
- Lei Wei (ORCID: https://orcid.org/0000-0003-0043-7600)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/cns.70106
- Citations
- 9
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 2.16
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Basic and Applied Basic Research Foundation of Guangdong Province