Libman-Sacks Endocarditis: A Silent Threat Unveiled by Stroke in a Young Female with Antiphospholipid Antibody Syndrome – A Case Report and Review of Literature

Libman–Sacks endocarditis (LSE) is a non-bacterial thrombotic endocarditis associated with systemic hypercoagulable states such as primary antiphospholipid antibody (APLA) syndrome and systemic lupus erythematosus. It is often missed due to its asymptomatic nature in the early stages. The vegetations in LSE are a potential source of embolism and can result in cerebrovascular accidents. Here, we report the case of a young female who presented with an embolic stroke and was diagnosed to have vegetation over the mitral valve. The patient was referred to our center for mitral valve replacement, but on detailed evaluation she was diagnosed as a case of LSE due to primary APLA syndrome. The patient was managed conservatively with anti-inflammatory drugs and anticoagulants.