Adipocyte-derived CXCL10 in obesity promotes the migration and invasion of ovarian cancer cells
Obesity exacerbates the production of CXCL10 from adipose tissues in obese women. CXCL10 is a key hub factor between developments of ovarian cancer and adipose tissues in obese. Targeting adipose-derived CXCL10 or its downstream macrophages may be a potential strategy to alleviate ovarian cancer accompanied by obesity.
Authors
- Lu Gao (ORCID: https://orcid.org/0000-0003-2170-2645)
- Qingjian Ou (ORCID: https://orcid.org/0000-0002-6881-8680)
- Zhe Wang (ORCID: https://orcid.org/0000-0002-5872-4306)
- Fanghai Han (ORCID: https://orcid.org/0000-0001-6698-8873)
- Yuanyuan Liu (ORCID: https://orcid.org/0000-0001-8107-9731)
- Ying Liu (ORCID: https://orcid.org/0000-0003-0552-2812)
- Jing Feng (ORCID: https://orcid.org/0000-0001-9805-0353)
- Qingwei Zhu
Institutions
- Tongji University (CN)
- Shanghai Medical College of Fudan University (CN)
- Bengbu Medical College (CN)
- Institut de Médecine de la Reproduction (FR)
- Tongji Hospital (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2024-12-19
- DOI
- https://doi.org/10.1186/s13048-024-01568-0
- Citations
- 4
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China