Utero-placental (vascular) development throughout pregnancy in women with polycystic ovary syndrome: the Rotterdam Periconceptional Cohort
Women with PCOS show decreased first-trimester placental development at 11 weeks' GA compared with pregnancies without PCOS in the subfertile and fertile group. Additionally, these women also display lower UtA PI and UtA RI compared with women without PCOS. These results support the hypothesis that PCOS impacts early placental development, potentially contributing to adverse pregnancy outcomes. Further research should focus on the underlying pathophysiology and the modifying role of IVF/ICSI treatment.
Authors
- Lawrence Berns
- Régine P.M. Steegers‐Theunissen (ORCID: https://orcid.org/0000-0002-4353-5756)
- Rosalieke E. Wiegel
- Sten P. Willemsen (ORCID: https://orcid.org/0000-0002-1675-2931)
- Anton H. J. Koning (ORCID: https://orcid.org/0000-0002-3147-0887)
- Joop S.E. Laven (ORCID: https://orcid.org/0000-0002-5444-9845)
Institutions
- Erasmus MC (NL)
Publication Details
- Journal
- F&S Reports
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1016/j.xfre.2024.12.002
- Citations
- 3
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Erasmus Medisch Centrum