Evaluation of Blue®m Mouthwash vs. Chlorhexidine Mouthwash in Patients with Gingivitis—A Pilot Study

Chlorhexidine is widely regarded as a gold standard antiplaque agent, and it is used commonly in periodontal patients. However, due to its side effects, a suitable alternative agent has been searched for several years. The present study compared the efficacy of a novel, oxygen-releasing, natural mouthwash Blue®m (Bluem Europe, Zwolle, The Netherlands) with chlorhexidine in patients with gingivitis. A total of 50 patients were selected and randomly divided into two groups who received a baseline scaling by a trained periodontist. The test group received Blue®m mouthwash as an adjunct for 2 weeks, whereas the control group received chlorhexidine mouthwash for 2 weeks. The primary outcomes of the Full-Mouth Gingival Index, Full-Mouth Plaque Index, and a percentage of the bleeding sites were recorded at the baseline. The same parameters were recorded after 2 weeks and 1 month from the baseline. Both the study and control groups exhibited equal efficacy in terms of reduction in the gingival index and bleeding percentage, both at 2 weeks and 1 month post scaling. However, the Blue®m group displayed statistically significant reduction in plaque index at 1 month as compared with chlorhexidine. As per the objectives of the study, it can be concluded that Blue®m reported a better antiplaque efficacy compared with chlorhexidine.