Longitudinal trajectory of plasma p-tau217 in cognitively unimpaired subjects
In amyloid-negative cognitively unimpaired subjects, ApoE4 status influenced both baseline levels and rate of change of plasma p-tau217. Other factors such as age, sex or glomerular filtration rate have not shown significant influence on plasma p-tau217 levels in this group.
Authors
- Marta Drake-Pérez (ORCID: https://orcid.org/0000-0002-4049-2885)
- Eloy Rodríguez‐Rodríguez (ORCID: https://orcid.org/0000-0001-7742-677X)
- Juan Irure‐Ventura (ORCID: https://orcid.org/0000-0003-2315-8671)
- Maria Teresa Garcı́a-Unzueta (ORCID: https://orcid.org/0000-0003-2531-3284)
- Marcos López‐Hoyos (ORCID: https://orcid.org/0000-0003-0562-427X)
- Francisco Martínez‐Dubarbie (ORCID: https://orcid.org/0000-0002-1482-7813)
- María Mercedes Bravo (ORCID: https://orcid.org/0000-0002-6472-8362)
- Sara López‐García (ORCID: https://orcid.org/0000-0002-7888-8850)
- Carmen Lage (ORCID: https://orcid.org/0000-0003-1703-121X)
- Pascual Sánchez‐Juan
- Andrea Corrales‐Pardo
- Enrique Marco de Lucas (ORCID: https://orcid.org/0000-0002-5310-7245)
- Marta Fernández‐Matarrubia (ORCID: https://orcid.org/0000-0002-6732-2691)
- Ana Pozueta‐Cantudo
- Armando Ruiz (ORCID: https://orcid.org/0000-0001-8896-8611)
- María García‐Martínez (ORCID: https://orcid.org/0009-0004-5422-1842)
Institutions
- Universidad de Cantabria (ES)
- Instituto de Salud Carlos III (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- Marqués de Valdecilla University Hospital (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
- Fundacion Centro De Investigacion De Enfermedades Neurologicas (ES)
- Global Brain Health Institute (US)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2024-12-20
- DOI
- https://doi.org/10.1186/s13195-024-01642-1
- Citations
- 5
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.63