SOX9 Overexpression Ameliorates Metabolic Dysfunction-associated Steatohepatitis Through Activation of the AMPK Pathway
Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for treating MASH.
Authors
- Bonan Xu
- Fei Chen (ORCID: https://orcid.org/0000-0001-7890-0330)
- Juan Deng (ORCID: https://orcid.org/0000-0002-2206-9960)
- Xin Zhang (ORCID: https://orcid.org/0000-0003-4243-8396)
- Shuqing Liu
- Wei‐Fen Xie (ORCID: https://orcid.org/0000-0002-7137-112X)
- Kai Ding (ORCID: https://orcid.org/0000-0001-9475-437X)
- Ru Huang
Institutions
- Shanghai Changzheng Hospital (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2024-12-20
- DOI
- https://doi.org/10.14218/jcth.2024.00197
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Natural Science Foundation of China